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KMID : 1144820180240020087
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대한의생명과학회지
2018 Volume.24 No. 2 p.87 ~ p.93
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Effects of Houttuynia cordata Extracts of Different Aerial Parts on Antioxidants and Anti-inflammatory
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Lee Sung-Gyu
Kang Hyun
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Abstract
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The current study was carried out to determine the effects of the leaf and root of Houttuynia cordata Thunb on antioxidant and anti-inflammatory. Total polyphenol contents of leaf and root ethanol extracts were found to be 59.32 and 12.07 mg/g, respectively. Also, total flavonoid contents of leaf and root ethanol extracts were found to be 10.85 and 8.55 mg/g, respectively. The RC50 values of DPPH radical scavenging of leaf and root ethanol extracts were 23.51 and 154.72 μg/mL, respectively. The RC50 values of ABTS radical scavenging of leaf and root ethanol extracts were 35.42 and 233.89 μg/mL, respectively. The antioxidant activities in leaf ethanol extracts were higher in root. Also, to confirm anti-inflammatory activity of ethanol extract, we treat leaf and root of Houttuynia cordata Thunb extract on BV-2 cell with LPS. The NO inhibition effects in of Houttuynia cordata Thunb leaf ethanol extracts showed higher values compared with the root ethanol extracts. These results indicate that Houttuynia cordata Thunb ethanol extracts may play a positive role in antioxidant and anti-inflammatory.
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KEYWORD
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Houttuynia cordata, Leaf, Polyphenol, BV-2, Antioxidant
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